Daxxify vs Botox: The Differences in Cosmetic Treatments

daxxify vs botox

When it comes to reducing wrinkles and achieving a more youthful appearance, Daxxify and Botox are two popular options that people often consider. Both treatments aim to achieve similar results but have some key differences.

Understanding Daxxify and Botox

To get a gist of the difference between Botox and Daxxify, you first need to understand what each procedure means:

What is Daxxify?

A relatively new cosmetic procedure called Daxxify includes injecting a specially-made solution into the skin to get rid of wrinkles and fine lines. The solution used in Daxxify contains a mix of peptides, vitamins, and other ingredients that stimulate collagen production and improve skin elasticity.

The U.S. Food and Drug Administration (FDA) has cleared Daxxify, an injectable drug that is meant to smooth out wrinkles on adults’ faces. Dermatologists see this approval as a big deal because it means Botox will have its first major rival in decades.

Neuromodulators are the chemical group that Daxxify is in. Other well-known neuromodulators are Botox, Dysport, Xeomin, and Jeuveau. The American Society for Dermatologic Surgery (ASDS) says that the benefits of these well-known neuromodulators last for about three months on average.

What makes Daxxify unique is that it might help reduce wrinkles for a longer time. In clinical studies that were sent to the FDA, 80% of people who used Daxxify had no or few wrinkles on their faces after four months, and about half of those people still had few wrinkles at six months.

What is botox?

Botox injections involve the use of a toxin to temporarily stop a muscle from moving. People often use them to get rid of wrinkles on their faces, but they can also help with neck spasms, headaches, an overactive bladder, lazy eyes, and excessive sweating.

Botox’s toxin comes from the same place that botulism, a type of food poisoning, does. However, the FDA has very strict rules about how the pure types of botulinum toxin that are used in Botox injections must be used. As long as licensed medical professionals use these poisons correctly, they are secure and won’t harm you.

Daxxify vs. Botox: The Comparison

Daxxify and Botox are similar in their mechanisms of action and the results they deliver. Both are neuromodulators that work by relaxing specific muscles responsible for wrinkles when they contract. They are highly effective in addressing various signs of aging.

However, there are notable differences between Botox and Daxxify:

  • Duration of Results: The effects of Daxxify last longer than Botox. They usually last 6–9 months, while Botox only lasts 3–4 months. This is because Daxxify is made especially; it has a protein in it that makes the poison work longer, which Botox doesn’t have.
  • Types of Wrinkles Addressed: There are some lines and wrinkles that Botox can treat, such as frown lines, forehead lines, and crow’s feet. On the other hand, the FDA has only approved Daxxify for glabellar lines as of right now.
  • Formulation and Dosage: While both are neuromodulators, Daxxify and Botox have different formulations and are distinct medications. The minimum recommended dose for Daxxify is 40 units for glabellar lines, compared to Botox’s 20 units.
  • Market Presence: Daxxify is a newer entrant in the market, having been FDA-approved in 2022. On the other hand, Botox has been legal since 2002 and has been in use by many people for more than 20 years.
  • Cost: Daxxify is typically more expensive per unit than Botox, but its longer-lasting results mean fewer treatments are needed per year, potentially making it a more cost-effective option in the long run.

While Daxxify and Botox share similarities, including their effectiveness in treating wrinkles, they differ in terms of result duration, types of wrinkles treated, formulation, market presence, and cost. Because everyone is different and has different wants and preferences, each treatment may be better for some people than others.

Advantages and Disadvantages


Daxxify’s skin rejuvenation benefits are notable for its lack of human serum albumin or animal-based components, unlike Botox. Instead, Daxxify utilizes a peptide exchange technology for longer-lasting effects and a safer, more natural option. However, there are potential drawbacks such as bruising, headaches, or eyelid ptosis. As individual responses can vary, consulting a dermatologist before use is advisable.


Botox effectively reduces wrinkles by temporarily paralyzing the muscles responsible for dynamic wrinkles, resulting in smoother, younger-looking skin. While generally safe, Botox can cause short-term side effects like bruising, swelling, or muscle weakness at the injection site. In rare cases, asymmetry or over-relaxation of muscles may occur, emphasizing the importance of professional administration.

Safety and Potential Risks


A lot of research has shown that Daxxify is a safe alternative to Botox because it can slow down the aging process caused by mild to heavy muscle movement. Daxxify is different from other neuromodulators because it stays stable at room temperature, so it doesn’t need to be kept cold.


Botox has been shown to be safe when used by trained experts. It is used in medicine for things other than looks, like headaches and too much sweating. Proper administration and dosages are crucial to minimizing risks like temporary asymmetry or muscle over-relaxation.

Duration of Results and Maintenance

Longevity of Daxxify’s Effects

The effects of Daxxify usually last between 6 and 9 months. During this time, your face will look better and have fewer wrinkles. It starts working faster and lasts longer than Botox. You can usually see big differences within two days.

Factors affecting longevity: How long Daxxify’s benefits last depends on your skin type, age, genes, and things in the environment like UV rays and pollution. A healthy diet and good skin care habits can help get the best results.

Longevity of Botox’s Effects

Botox smooths out skin and stops muscles from tensing up for three to four months. To maintain the effects, you need to get follow-up treatments every couple of months, depending on how well you respond.

Influencing factors: Botox’s benefits can last longer or shorter depending on your lifestyle, how you use your body, how fast your body breaks down toxins, and how much sun you get. Regular care can help keep wrinkles from coming back.

Daxxify vs. Botox: The Price

While the initial cost of a Daxxify treatment is higher than that of Botox in most practices, Daxxify’s longer-lasting effects make it a more cost-effective option in the long run. For instance, if a Botox client typically spends $1600 annually on four $400 treatments every three months, a

Daxxify clients would spend $1200 annually on two $600 treatments every six months. These figures are approximate and can vary based on practice and location, but they illustrate why Daxxify is often considered the more economical choice over time.

Is Daxxify better than Botox?

The choice between Daxxify and Botox ultimately depends on your individual needs and preferences. If you are looking for a more natural alternative to Botox and are willing to invest in a more expensive treatment, Daxxify may be a good option for you. However, if you are looking for a quick and effective solution for reducing wrinkles, Botox may be the better choice.

Botox and Daxxify are both good ways to get rid of lines and make your skin feel better. They are different, though, in how well they work, how safe they are, and how much they cost. Talking to a trained professional is important to figure out which treatment will work best for you based on your wants and goals.

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